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TxGemma

GoogleOpen WeightsPending Human Review

TxGemma is an open-weight Gemma 2 specialization fine-tuned for therapeutic development. It uses natural language, chemical SMILES, protein and nucleic-acid sequences to predict properties of therapeutic entities and targets. Prediction checkpoints prioritize task accuracy; the 9B and 27B chat variants add explanations and multi-turn dialogue. The family is a research and development foundation under Health AI Developer Foundations terms.

2025-03-25
2B, 9B and 27B
Gemma 2 decoder-only Transformer
Health AI Developer Foundations terms of use

Specifications

Parameters
2B, 9B and 27B
Architecture
Gemma 2 decoder-only Transformer
License
Health AI Developer Foundations terms of use
Type
text
Modalities
text

Benchmark Scores

Advanced Specifications

Model Family
Gemma
Finetuned From
gemma-2
API Access
Not Available
Chat Interface
Not Available
Variants
txgemma-2b-predicttxgemma-9b-predicttxgemma-27b-predicttxgemma-9b-chattxgemma-27b-chat
Hardware Support
GPUTPUCPU

Capabilities & Limitations

Capabilities
therapeutic property predictionbiomedical reasoningconversational explanations
Known Limitations
Predictions need task-specific validation and experimental confirmation.Chat variants trade some raw predictive accuracy for conversational flexibility.
Notable Use Cases
drug-discovery researchtarget and molecule assessmenttherapeutics modeling

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